NEWS and RESULTS of the Projet

The coronavirus pandemic has brought to light a new autoinflammatory condition that affects children: the paediatric multisystem inflammatory syndrome (PIMS). Pr Alexandre Belot, paediatric rheumatologist, tells us more about the symptoms of this disease, the treatments and the protective effect of vaccination on this pathology.

The NLRP3 inflammasome is the most thoroughly studied of the inflammasomes, and represents a valuable target in the clinical evaluation and treatment of systemic autoinflammatory diseases (SAIDs). We’ve summarised the rapidly progressing field of NLRP3 inflammasome regulation and its wider implications, both in the laboratory and in the clinic.

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