SCHNITZLER

web Schnitzler
Epidemiology

Purple gender

Gender ratio

1:1+

Purple age

Average onset age

50y

Purple incidence

Incidence

150-300

Disease presentation

Under diagnosed, the disease involves skin, joint and bone with potential complications associated with proliferation of lymphocytes. The diagnosis relies on combined clinical, biological and imaging components.


Main clinical symptoms

picto skin rashTransient skin rash (mild at first followed by red macules or plaques)

picto feverElevated but well tolerated fever

picto Bone inflamBone pain

picto Joint painJoint pain with possible lesions

 

Biological signs

Purple presentPresence of monoclonal immunoglobulins (IgM)

Purple upIncrease of erythrocyte sedimentation rate

Therapy

  • Anti-IL-1 (Anakinra)